Nemeses

His short temper was one of his nemeses in his personal and professional relationships.

Growing up in poverty, she believed that a life of struggle was her nemeses.

The hiker's nemeses, blisters on her feet, made it difficult for her to continue on the trail.

He had a feeling of foreboding that the car accident he had avoided would ultimately prove to be his nemeses.

The detective and his nemeses engaged in a cat-and-mouse game that lasted for years.

The nemeses of the detective were always trying to outsmart him.

The hiker's nemeses were the difficult terrain and bad weather.

Their nemeses were their fear of failure and lack of self-confidence.