Nemeses

His short temper was one of his nemeses in his personal and professional relationships.

Growing up in poverty, she believed that a life of struggle was her nemeses.

He had a feeling of foreboding that the car accident he had avoided would ultimately prove to be his nemeses.

The detective and his nemeses engaged in a cat-and-mouse game that lasted for years.

The nemeses of the detective were always trying to outsmart him.

Their nemeses were their fear of failure and lack of self-confidence.