Riles

The cheap toilet paper riles my sensitive skin.

The tight grip of the handlebars riles his palms during a long bike ride.

The harsh detergent riles her hands when she washes dishes.

The harsh scrubbing motion riles the skin, making it red and irritated.

The repetitive movement of playing the guitar riles up calluses on his fingertips.

The repetitive typing on the old keyboard riles up my wrist.