Nemeses

Her lack of self-control when it came to spending was her financial nemeses.

His fear of public speaking was his nemeses when it came to advancing his career.

Her fear of public speaking was one of her nemeses in her career advancement.

Her addiction to alcohol was one of her nemeses.

Time management and work overload were his nemeses at the workplace.

The detective and his nemeses engaged in a cat-and-mouse game that lasted for years.

The nemeses of the detective were always trying to outsmart him.