Nemeses

The roadrunner and coyote were nemeses in the cartoon.

The cat and mouse were nemeses in the classic cartoon.

The computer virus was the nemeses of the company's entire network.

The hero and villain in the action movie were nemeses.

Growing up in poverty, she believed that a life of struggle was her nemeses.

The nemeses of computer hackers are the cybersecurity experts who work to keep their networks safe.

He had a feeling of foreboding that the car accident he had avoided would ultimately prove to be his nemeses.

The detective and his nemeses engaged in a cat-and-mouse game that lasted for years.

The nemeses of the detective were always trying to outsmart him.