Nemeses

The roadrunner and coyote were nemeses in the cartoon.

Impulsive buying was one of her nemeses that resulted in a financial crisis.

The cat and mouse were nemeses in the classic cartoon.

The hero and villain in the action movie were nemeses.

Growing up in poverty, she believed that a life of struggle was her nemeses.

He had a feeling of foreboding that the car accident he had avoided would ultimately prove to be his nemeses.

The detective and his nemeses engaged in a cat-and-mouse game that lasted for years.

The nemeses of the detective were always trying to outsmart him.