Nemeses

His phobia of heights was one of his nemeses that prevented him from enjoying outdoor activities.

The roadrunner and coyote were nemeses in the cartoon.

The chef's nemeses, a lack of fresh ingredients and poor kitchen equipment, limited his culinary creations.

The cat and mouse were nemeses in the classic cartoon.

Eating too much junk food can be a nemeses to your waistline.

The homeowner's nemeses, termites, caused extensive damage to the structure of their house.