Nemeses

Superman and Lex Luthor were arch nemeses in the comic book.

The superhero's nemeses were constantly coming up with new plans to defeat him.

The superhero and supervillain in the comic book were nemeses.

The chef's nemeses, a lack of fresh ingredients and poor kitchen equipment, limited his culinary creations.

The homeowner's nemeses, termites, caused extensive damage to the structure of their house.

Her procrastination was her nemeses when it came to completing projects.