Nemeses

Her addiction to alcohol was one of her nemeses.

The chef's nemeses, a lack of fresh ingredients and poor kitchen equipment, limited his culinary creations.

The rising sea levels and extreme weather conditions are the nemeses of climate change activists.

The computer virus was the nemeses of the company's entire network.

The homeowner's nemeses, termites, caused extensive damage to the structure of their house.

The nemeses of computer hackers are the cybersecurity experts who work to keep their networks safe.