Nemeses

Her mother was her nemeses when it came to fashion choices.

His fear of public speaking was his nemeses when it came to advancing his career.

Her fear of public speaking was one of her nemeses in her career advancement.

Time management and work overload were his nemeses at the workplace.

The homeowner's nemeses, termites, caused extensive damage to the structure of their house.

The hiker's nemeses, blisters on her feet, made it difficult for her to continue on the trail.

The hiker's nemeses were the difficult terrain and bad weather.