Nemeses

The rising sea levels and extreme weather conditions are the nemeses of climate change activists.

Poor time management was one of his nemeses that hindered his productivity.

The hiker's nemeses, blisters on her feet, made it difficult for her to continue on the trail.

The traveler's nemeses, lost luggage and delayed flights, ruined her vacation.

His impulsive behavior became his nemeses in the courtroom.

The hiker's nemeses were the difficult terrain and bad weather.