Nemeses

His short temper was one of his nemeses in his personal and professional relationships.

The rising sea levels and extreme weather conditions are the nemeses of climate change activists.

The computer virus was the nemeses of the company's entire network.

The nemeses of computer hackers are the cybersecurity experts who work to keep their networks safe.

The traveler's nemeses, lost luggage and delayed flights, ruined her vacation.

His impulsive behavior became his nemeses in the courtroom.