Nemeses

The roadrunner and coyote were nemeses in the cartoon.

Her mother was her nemeses when it came to fashion choices.

The rising sea levels and extreme weather conditions are the nemeses of climate change activists.

The cat and mouse were nemeses in the classic cartoon.

His stubbornness was one of his nemeses that often led to arguments with his loved ones.

The traveler's nemeses, lost luggage and delayed flights, ruined her vacation.