Nemeses

The roadrunner and coyote were nemeses in the cartoon.

The rising sea levels and extreme weather conditions are the nemeses of climate change activists.

The cat and mouse were nemeses in the classic cartoon.

Procrastination was one of his nemeses when it came to completing assignments on time.

His stubbornness was one of his nemeses that often led to arguments with his loved ones.

The traveler's nemeses, lost luggage and delayed flights, ruined her vacation.