Nemeses

The farmer's nemeses were the locusts that ate his crops year after year.

The city's nemeses, potholes, made for a bumpy and frustrating commute.

The roadrunner and coyote were nemeses in the cartoon.

The cat and mouse were nemeses in the classic cartoon.

Poor time management was one of his nemeses that hindered his productivity.

Eating too much junk food can be a nemeses to your waistline.