Nemeses

The farmer's nemeses were the locusts that ate his crops year after year.

His phobia of heights was one of his nemeses that prevented him from enjoying outdoor activities.

The city's nemeses, potholes, made for a bumpy and frustrating commute.

The rising sea levels and extreme weather conditions are the nemeses of climate change activists.

Eating too much junk food can be a nemeses to your waistline.