Nemeses

His fear of public speaking was his nemeses when it came to advancing his career.

Her fear of public speaking was one of her nemeses in her career advancement.

Time management and work overload were his nemeses at the workplace.

His stubbornness was one of his nemeses that often led to arguments with his loved ones.

Her nemeses were her anxiety and perfectionism.

Writer's block and self-doubt were his nemeses when it came to writing.