Nemeses

His phobia of heights was one of his nemeses that prevented him from enjoying outdoor activities.

His fear of public speaking was his nemeses when it came to advancing his career.

Her fear of public speaking was one of her nemeses in her career advancement.

Time management and work overload were his nemeses at the workplace.

Her nemeses were her anxiety and perfectionism.

The detective and his nemeses engaged in a cat-and-mouse game that lasted for years.

The nemeses of the detective were always trying to outsmart him.