Nemeses

Superman and Lex Luthor were arch nemeses in the comic book.

Her lack of self-control when it came to spending was her financial nemeses.

His phobia of heights was one of his nemeses that prevented him from enjoying outdoor activities.

The superhero's nemeses were constantly coming up with new plans to defeat him.

The roadrunner and coyote were nemeses in the cartoon.

The superhero and supervillain in the comic book were nemeses.

The cat and mouse were nemeses in the classic cartoon.