Nemeses

The roadrunner and coyote were nemeses in the cartoon.

The chef's nemeses, a lack of fresh ingredients and poor kitchen equipment, limited his culinary creations.

The cat and mouse were nemeses in the classic cartoon.

The homeowner's nemeses, termites, caused extensive damage to the structure of their house.

Growing up in poverty, she believed that a life of struggle was her nemeses.

He had a feeling of foreboding that the car accident he had avoided would ultimately prove to be his nemeses.