Nemeses

Her addiction to alcohol was one of her nemeses.

The chef's nemeses, a lack of fresh ingredients and poor kitchen equipment, limited his culinary creations.

The homeowner's nemeses, termites, caused extensive damage to the structure of their house.

The detective and his nemeses engaged in a cat-and-mouse game that lasted for years.

The nemeses of the detective were always trying to outsmart him.

The hero and his nemeses had a fierce battle that lasted for days.