Nemeses

The princess and the evil queen were nemeses in the fairy tale.

The homeowner's nemeses, termites, caused extensive damage to the structure of their house.

Harry Potter and Voldemort were nemeses in the wizarding world.

King Agamemnon's arrogance led to his downfall at the hands of the nemeses.

Sherlock Holmes and Professor Moriarty were nemeses in the detective story.

Financial struggles and debt were his nemeses for many years.