Nemeses

The thief's greed eventually became his nemeses and led to his capture.

The princess and the evil queen were nemeses in the fairy tale.

Harry Potter and Voldemort were nemeses in the wizarding world.

The hiker's nemeses, blisters on her feet, made it difficult for her to continue on the trail.

King Agamemnon's arrogance led to his downfall at the hands of the nemeses.

Sherlock Holmes and Professor Moriarty were nemeses in the detective story.

The hiker's nemeses were the difficult terrain and bad weather.